Order 2026-112-02-01 Amending the Domestic Substances List: SOR/2026-27
Canada Gazette, Part II, Volume 160, Number 4
Registration
SOR/2026-27 February 16, 2026
CANADIAN ENVIRONMENTAL PROTECTION ACT, 1999
Whereas the Minister of the Environment has been provided with information under section 106footnote a or 107footnote b of the Canadian Environmental Protection Act, 1999footnote c, and any additional information or test results required under subsection 109(1) of that Act, in respect of each of the living organisms referred to in the annexed Order;
Whereas the Minister of the Environment and the Minister of Health are satisfied that the living organisms have been manufactured in or imported into Canada by the person who provided the information prescribed by the New Substances Notification Regulations (Organisms)footnote d;
Whereas the period for assessing the information under section 108 of that Act has expired;
And whereas no conditions specified under paragraph 109(1)(a) of that Act in respect of the living organisms are in effect;
Therefore, the Minister of the Environment makes the annexed Order 2026-112-02-01 Amending the Domestic Substances List under subsection 112(1) of the Canadian Environmental Protection Act, 1999 footnote c.
Ottawa, February 12, 2026
Julie Dabrusin
Minister of the Environment
Order 2026-112-02-01 Amending the Domestic Substances List
Amendments
1 Part 5 of the Domestic Substances List footnote 1 is amended by adding the following in alphabetical order under the heading “Organisms/Organismes”:
Recombinant, chimeric vesicular stomatitis virus carrying the envelope glycoprotein of the visceral non-neurotropic WE-HPI strain of the lymphocytic choriomeningitis virus N
| 19809-7 N | Saccharomyces species, YS393-C5 |
|---|
Coming into Force
3 This Order comes into force on the day on which it is registered.
REGULATORY IMPACT ANALYSIS STATEMENT
(This statement is not part of the orders.)
Issues
The Minister of the Environment and the Minister of Health (the Ministers) assessed information on seven substances (five chemicals and polymers and two living organisms) and determined that they meet the criteria for addition to the Domestic Substances List, as set out in the Canadian Environmental Protection Act, 1999 (the Act). Therefore, under the authority of sections 87 and 112 of the Act, the Minister of the Environment (the Minister) is adding these seven substances to the Domestic Substances List.
Background
Assessment of substances new to Canada
Substances that are not on the Domestic Substances List are considered new to Canada and are subject to notification and assessment requirements set out in sections 81, 83, 106 and 108 of the Act, as well as in the New Substances Notification Regulations (Chemicals and Polymers) and the New Substances Notification Regulations (Organisms). The Act and these regulations ensure that new substances introduced to the Canadian marketplace are assessed to identify potential risks to the environment and human health, and that appropriate control measures are taken, if deemed necessary.
For more information on the thresholds and scope of these regulations, please see section 1 in the Guidance document for the New Substances Notification Regulations (Chemicals and Polymers) and section 2 of the Guidelines for the Notification and Testing of New Substances: Organisms.
Domestic Substances List
The Domestic Substances List (SOR/94-311) provides an inventory of substances in the Canadian marketplace. It was originally published in the Canada Gazette, Part II, in 1994 and its current structure was established in 2001 (Order 2001-87-04-01 Amending the Domestic Substances List [SOR/2001-214]). The Domestic Substances List is amended, on average, 12 times per year to add, update or delete substances.
The Domestic Substances List includes eight parts, in which substances are divided based on
- substance type (chemicals and polymers or inanimate products of biotechnology and living organisms);
- confidentiality; and
- whether the significant new activity provisions of the Act have been applied.
Adding substances to the Domestic Substances List
New substances must be added to the Domestic Substances List under subsection 87(1), 87(5) or 112(1) of the Act within 120 days after the following criteria have been met:
- the Minister has been provided with the regulatory information regarding the substance. The information to be provided is set out in the New Substances Notification Regulations (Chemicals and Polymers) and the New Substances Notification Regulations (Organisms);
- the period prescribed under section 83 or 108 of the Act for the assessment of the information submitted for the substance has expired;
- the substance is not subject to any conditions imposed under paragraph 84(1)(a) or 109(1)(a) of the Act on its import or manufacture; and
- for additions under subsection 87(1), the Ministers are satisfied that the substance has already been manufactured in, or imported into Canada in excess of the prescribed quantity by the person who provided the information; for additions under subsection 112(1), the Ministers are satisfied that the substance has already been manufactured in, or imported into Canada by the person who provided the information.
Adding seven substances to the Domestic Substances List
The Ministers assessed information on seven substances new to Canada (five chemicals and polymers and two living organisms) and determined that they meet the criteria for addition to the Domestic Substances List, under subsection 87(5) or 112(1) of the Act. These seven substances are therefore being added to the Domestic Substances List and, as a result, are no longer subject to the New Substances Notification Regulations (Chemicals and Polymers), nor to the New Substances Notification Regulations (Organisms).
Objective
The objective of Order 2026-87-02-01 Amending the Domestic Substances List (Order 2026-87-02-01) is to add five chemicals and polymers to the Domestic Substances List.
The objective of Order 2026-112-02-01 Amending the Domestic Substances List (Order 2026-112-02-01) is to add two living organisms to the Domestic Substances List.
Order 2026-87-02-01 and Order 2026-112-02-01 (the orders) are expected to facilitate access to seven substances for businesses, as the substances are no longer subject to requirements under subsection 81(1) or 106(1) of the Act.
Description
Order 2026-87-02-01 is made under subsection 87(5) of the Act to add five chemicals and polymers to the Domestic Substances List:
- two substances identified by their Chemical Abstracts Service (CAS) Registry Numbersfootnote 2 are added to Part 1 of the Domestic Substances List; and
- three substances identified by their masked namesfootnote 3 and their Confidential Accession Numbersfootnote 4 (CANs) are added to Part 3 of the Domestic Substances List.
Order 2026-112-02-01 is made pursuant to subsection 112(1) of the Act to add two living organisms to the Domestic Substances List:
- one living organism identified by its specific substance name is added to Part 5 of the Domestic Substances List; and
- one living organism identified by its masked name and its CAN is added to Part 7 of the Domestic Substances List.
Regulatory development
Consultation
As the Act does not prescribe any public comment period before adding a substance to the Domestic Substances List, no consultation period for the orders was deemed necessary.
Indigenous engagement, consultation and modern treaty obligations
Orders amending the Domestic Substances List do not introduce any new regulatory requirements, and therefore, do not result in any impact on modern treaty rights or obligations. As a result, specific engagement and consultations with Indigenous peoples were not undertaken.
Instrument choice
Under the Act, the Minister is required to add a substance to the Domestic Substances List when it is determined to meet the criteria for addition. Orders amending the Domestic Substances List are the only regulatory instruments that allow the Minister to comply with these obligations.
Regulatory analysis
Benefits and costs
Adding substances on the Domestic Substances List is administrative in nature. The orders do not impose any regulatory requirements on businesses and, therefore, do not result in any incremental compliance costs for stakeholders or enforcement costs for the Government of Canada. Adding substances to the Domestic Substances List is a federal obligation under section 87 or 112 of the Act that is triggered once a substance meets the criteria for addition.
Small business lens
As described in the “Benefits and costs” section, the orders will not result in any incremental impacts. As a result, the orders will not impact Canadian small businesses and the small business lensfootnote 5 was not applied.
One-for-one rule
Since the orders do not impose any regulatory requirements (see “Benefits and costs” section), they do not impose new administrative burden on business and the one-for-one rule does not apply.
Regulatory cooperation and alignment, and international obligations
There are no international agreements or obligations directly associated with the orders.
Effects on the environment
In accordance with the Cabinet Directive on Strategic Environmental and Economic Assessment, a strategic environmental and economic assessment (SEEA) is required for proposals that are expected to have important effects (positive or negative, direct or indirect) on the environment and economy. Since orders amending the Domestic Substances List to add substances do not result in incremental impacts (benefits and costs), a SEEA is not required.
Right to a healthy environment
The Government of Canada has a duty, in the administration of the Act, to protect the right to a healthy environment, as provided for under the Act, subject to reasonable limits. An implementation framework sets out considerations to protect this right and uphold the principles described in the framework.
Work to inform the orders was completed in part before the implementation framework was published on July 19, 2025. Recognizing that decisions made under the Act are informed by analyses and consultations that are often the result of years of work, a transition period is in place to allow the Department of the Environment and the Department of Health to support continued protection of the environment and human health. The objective of the transition period is to continue to advance timely decisions under the Act and actions while consideration of the right to a healthy environment and relevant principles are being fully integrated into the administration of the Act. The orders are proceeding under the transition period referenced in the framework.
Although the implementation framework was not available to be applied from the beginning of the work undertaken to inform the orders, many of the elements included in the framework were considered to inform the orders, such as the addition of new substances to the Domestic Substances List aligns with the framework by conducting an initial screening and review of the information submitted for new substances under the Act, prior to their use in Canada, to determine whether the new substances may pose a risk to the environment and human health and warrant further assessment under the Act.
Gender-based analysis plus
No gender-based analysis plusfootnote 6 (GBA+) impacts have been identified for the orders.
Implementation, compliance and enforcement, and service standards
Implementation
The orders are now in force. Developing an implementation plan is not required when adding substances to the Domestic Substances List. The orders do not constitute an endorsement from the Government of Canada of the substances to which they relate, nor an exemption from any other laws or regulations that are in force in Canada and that may apply to these substances or to activities involving them.
Compliance and enforcement
Where a person has questions concerning their obligation to comply with an order, believes that they may be out of compliance, or would like to request a prenotification consultation, they are encouraged to contact the Substances Management Information Line at substances@ec.gc.ca (email), 1‑800‑567‑1999 (toll-free in Canada), or 819‑938‑3232 (outside of Canada).
The orders are made under the authority of the Act, which is enforced in accordance with the Canadian Environmental Protection Act: compliance and enforcement policy. In instances of non-compliance, consideration is given to factors such as the nature of the alleged violation, effectiveness in achieving compliance with the Act and its regulations, and consistency in enforcement when deciding which enforcement measures to take. Suspected violations can be reported to the Enforcement Branch of the Department of the Environment by email at enviroinfo@ec.gc.ca.
Contact
Marc Demers
Acting Director
Regulatory Operations, Policy and Emerging Sciences Division
Department of the Environment
Gatineau, Quebec
K1A 0H3
Substances Management Information Line:
1‑800‑567‑1999 (toll-free in Canada)
819‑938‑3232 (outside of Canada)
Email: substances@ec.gc.ca